MSB Neuro Plus 5th Generation
Move your mouse over image or click to enlarge
MSB Neuro Plus 5th Generation MSB Neuro Plus 5th Generation MSB Neuro Plus 5th Generation MSB Neuro Plus 5th Generation MSB Neuro Plus 5th Generation MSB Neuro Plus 5th Generation

MSB Neuro Plus 5th Generation

Rated 4.7 out of 5
Based on 37 reviews
    • About
    • Ingredients
    • Directions
    • Free of

    Read our Down Syndrome Report

    Click here to read more About MSB including its history, how it's made, and customization.

    Click here to download our in-depth E-book about our new formula!

    Click here to download our MSB Dosage & Product Duration Chart (includes ingredient list!). This handy chart will help you decide which size of MSB is most appropriate for you and how long each size of jar will last.

    Welcome to the 5th Generation of our MSB formula. This version reflects the most recent developments in research in the areas connecting trisomy 21 with microbiome health and cognitive function.

    Our MSB formula has been modified to maximize absorption of certain nutrients even in the presence of an unfavourable microbiome. Lipid soluble B1, or benfotiamine, has been added to the formula for this reason along with activated B6 (pyridoxal-5-phosphate). N-acetyl-cysteine has been added as the cysteine source as it is a more stable form than the amino acid cysteine. Selenomethioine has been added as our Selenium source for the added benefit of additional methionine in the formula. Resveratrol, a plant polyphenol and potent antioxidant, has been added to the formula as well as curcumin, a compound from the herb turmeric with anti-inflammatory properties.

    Monk Fruit (Aka Siraitia grosvenorii) is an extremely sweet small green fruit. Extracts made from the dried fruit have been used as a natural sweetener for thousands of years in Asia. The unique biochemistry of this natural fruit extract allows it to have over 250 times the sweetening strength of sucrose without containing any calories or having any negative impact on blood sugar levels. It has been extensively researched in glucose disorders such as diabetes with positive outcomes. A very small amount is added to our new MSB formula to ensure the best tasting flavours without any added sugars, sucrose, or artificial sweeteners!

    Medicinal Ingredients: per scoop)

    Acetyl-L-Carnitine 12.5 mg
    B1 (Benfotiamine) 11.25 mg
    Biotin 30 mcg
    Calcium (Calcium Chelate) 31.25 mg
    Vitamin C (Calcium Ascorbate) 150 mg
    B5 (Calcium Pantothenate) 37.5 mg
    Choline (Choline Citrate) 18.75 mg
    Chromium (Chromium Chelate) 25 mcg
    CoQ10 (PureSorb Q40) 7.5 mg
    Copper (Copper Sulfate) 0.2 mg
    Curcumin 5 mg
    Inositol 6.25 mg
    L-Methionine 25 mg
    L-Methylfolate (L-5-methyltetrahydrofolate) 150 mcg
    Alpha Lipoic Acid 2.5 mg
    Lutein 0.5 mg
    Lycopene 2.5 mg
    Magnesium (Magnesium Glycinate) 45 mg
    B12 (Methylcobalamin) 75 mcg
    Molybdenum 25 mcg
    N-Acetyl-Cysteine 18.75 mg
    B3 (Niacin) 1.25 mg
    B3 (Niacinamide) 17.25 mg
    Iodine (Potassium Iodide) 25 mcg
    B6 (Pyridoxal-5-Phosphate P5P) 6.25 mg
    Resveratrol 12.5 mg
    B2 (Riboflavin HCl) 7.5 mg
    Selenium (Selenomethionine) 25 mcg
    Glutathione (Setria Glutathione) 7.5 mg
    Betaine (Trimethylglycine) 25 mg
    Vitamin A (Acetate) 375 IU
    Vitamin D3 (Cholecalciferol) 250 IU
    Alpha Tocopherol (Succinate) 25 IU
    Gamma Tocopherol 3.75 mg
    Vitamin K2 (Menaquinone) 3.75 mcg
    Zinc (Zinc Glycinate) 5 mg


    Non-Medicinal ingredients (flavoured powders): natural flavouring, monk fruit.

    *Flavouring may have come into contact with nuts and tree nuts.


    2-3 years (12-14 kg)- 1/2 scoop;

    4-8 years (15-31 kg)- 1 scoop;

    9-13 years (32-50 kg)- 2 scoops;

    14+ years (>50 kg)- 4 scoops or 4 capsules;

    *For product duration please see chart below

    Formula should be mixed with food or liquid and given at mealtime. Dose may by divided among meals.

    When you first start on the MSB Neuro Plus 5th Generation, start with only a partial dose, and work up to the full dose over a period of 1-2 weeks. It can be mixed with liquids or moist foods such as juice, dairy-free yogurt, applesauce, pudding, etc.

    Store in the freezer or in a cool, dry place. DO NOT REFRIGERATE.

    Product Duration Chart:

    *not recommended to prevent product expiry

    **Children younger than 14 years often have trouble swallowing capsules

    Age/Weight 50gm Powder 100gm Powder 200gm Powder 240 Capsules
    2-3 years (12-14 kg) 114 days 230 days *see note **see note
    4-8 years (15-31 kg) 57 days 114 days *see note **see note
    9-13 years (32-50 kg) 28 days 57 days 115 days **see note
    14+ years (>50 kg) 14 days 29 days 57 days 60 days



    Manufactured in a licensed lab following Good Manufacturing Practises. Made with premium ingredients for quality and purity. No artificial colours or flavours. Gluten-Free.

    *Flavoured powders may have come into contact with nuts and/or tree nuts.


average rating 4.7 out of 5
Based on 37 reviews
  • 5 Stars
    29 Reviews
  • 4 Stars
    6 Reviews
  • 3 Stars
    1 Review
  • 2 Stars
    0 Reviews
  • 1 Star
    1 Review
95% of reviewers would recommend this product to a friend
Overall Quality
Rated 3 out of 5
Customer photos and videos
37 Reviews
Reviewed by LaSandra B., from United States
Verified Buyer
I don't recommend this product
Age Range
35 - 44
Rated 1 out of 5
Review posted

Doesn't taste good

Even in food I can't get my daughter to eat it.

Overall Quality
Rated 1 out of 5
Was this helpful?


Hi LaSandra,

Thank you for taking the time to provide us with your valuable feedback!

We are sorry to hear your daughter does not like the taste of the MSB that you ordered. We know oftentimes children can be quite picky with flavours which is why we offer a few different flavours to choose from.

Some of our customers tell us their child prefers the unflavoured version, mixed into a flavourful food to disguise the taste of the vitamins (these children often do not like the monk fruit sweetener that is used in the flavoured MSB).

We want you to be satisfied with your purchase and we would be happy to troubleshoot this issue with you! We would be happy to send you a different flavour/unflavoured jar to try, or a refund if you are unable to use the one you have and do not want to try another. Please send us a quick email at to let us know what you prefer.

Warmest regards,

The NutriChem Team

Reviewed by Betty W., from United States
I recommend this product
Age Range
55 - 64
Wellness Concerns
  • Focus
  • Energy
  • Aging
  • Sleep
Rated 5 out of 5
Review posted

Improved mental clarity

My daughter who has Down syndrome, has been on MSB for about 3 years now. Her teachers in school tell me they have noticed a big difference this past year in her ability to "stay connected" in the classroom. She doesn't "turn off" as much as she used to. She participates more, talks more, conversational turns have increased, and she answers questions more often. It's like some of the fog in her brain has lifted and her mental clarity has improved. She is understanding more of what is being said, talks and texts on the phone now, goes to movies with friends, and seems to understand them more, and is enjoying being a part of things that used to just "go over her head."

Overall Quality
Rated 5 out of 5
Was this helpful?
Reviewed by shelly q.
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

5 Stars


Was this helpful?
Reviewed by Umzima E.
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Excellent Product

Thank you so very much. My daughter has been using MSB Plus since she was 3 months old. She is now 21 years old and doing wonderful.

Was this helpful?
Reviewed by Shiro T.
Verified Buyer
I recommend this product
Rated 4 out of 5
Review posted


5th generation cost us almost double comparing with 4th generation. It%92s the only pity thing.

Was this helpful?