Deglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers. Licorice has been shown to inhibit several inflammatory enzymes, including both cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), decreasing the production of several potent inflammatory compounds, including prostaglandin E2, thromboxane B2, and leukotriene B4. Importantly, this inhibition is not due to glycyrrhizic acid, the component of licorice which has been removed in DGL, and which is associated with mineralocorticoid excess and hypertension. Another component of licorice, glabridin, has been shown to prevent lipopolysaccharide (LPS) induced production of inflammatory compounds, including nitric oxide and interleukin-1 beta, whereas glycyrrhizic acid has no effect.
Medicinal Ingredients: Each tablet contains:
|Deglycyrrhizinated Licorice 10:1 Extract (Glycyrrhiza glabra) (root)||400 mg|
Non-medicinal ingredients: Xylitol, microcrystalline cellulose, chocolate flavour, guar gum, cocoa powder, coconut flavour, purified water, stearic acid, vegetable grade magnesium stearate (lubricant), Stevia rebaudiana leaf.
Adults: Chew 1 tablet 20 minutes prior to each meal, or as directed by a health care practitioner.
Caution: Consult a health care practitioner if symptoms persist or worsen. Keep out of reach of children.
Do not use if seal is broken. For freshness, store in a cool, dry place.
Artificial preservatives, colours, and sweeteners; dairy, soy, wheat, gluten, and yeast.